I literally got my card this week. I have installed it into my A500 Plus and to be honest the install is so easy and straightforward.
1) Remove Your 68000 CPU
2) Remove your Kickstart ROM (believe it or not this is no longer needed)
3) Insert the Vampire into the CPU Socket.
4) Fire it up and you should get a kickstart screen
Here is my YouTube video from my channel showing me going through the basic install process!
From this point onwards I have installed a pre-setup Compact Flash Card (Sandisk is recommended for this) with Classic Workbench on it and then installed Picasso96 and the latest SAGA Driver as my card has already got the Gold 2 Core on it.